Stage II MMR-P & Stage III A/B

Oncotype DX Results: What to Expect

Because waiting for—and understanding—your cancer test results can be stressful, Genomic Health makes understanding your Oncotype DX Colon Recurrence Score test results as easy as possible.

Your results are available to your doctor in approximately two weeks after your tumor sample arrives at the Genomic Health laboratory. Your score shows how likely your cancer is to return in three years for stage II patients and five years for stage III A/B patients.1-4 You and your doctor can discuss the score (along with supporting information provided) and how it may affect your treatment choices.

Understanding your Colon Recurrence Score results

Your Colon Recurrence Score results appear in a report that gets sent to your doctor. The report provides your individualized result as a number between 0-100. A low score means there is a lower chance that the cancer will return, and a high score means there is a higher chance for a recurrence.1-4

Distribution of Recurrence Score Results (0-100)

Low High
A lower Recurrence Score result means:
your cancer is less likely to come back
A higher Recurrence Score result means:
your cancer is more likely to come back

You and your doctor can use this information to help plan your treatment options together. It’s important to understand that a low Recurrence Score result does not mean there is no chance your colon cancer will return. And, a high Recurrence Score result does not mean your colon cancer will definitely return. So, your treatment decisions still depend on your unique situation and personal preferences.

For stage II patients

Patients with stage II colon cancer who have a higher Colon Recurrence Score (indicating a higher risk) may benefit more from chemotherapy than those who have a lower score.

For stage III A/B patients

Patients with stage III A/B colon cancer who have a lower Colon Recurrence Score may benefit less from certain drugs added to chemotherapy than those who have a higher score.

How your score is generated

The Colon Recurrence Score test is a genomic test—it looks at the activity of your tumor’s genes. Your score is based on the behavior of specific genes in the tumor tissue removed during your surgery. Looking at this unique set of genes—how they are expressed—gives us information about how likely your cancer is to return.

Learn more about how the test works.

REFERENCES

1. Gray et al. J Clin Oncol. 2011.
2. Venook et al. J Clin Oncol. 2013.
3. Yothers et al. J Clin Oncol. 2013.
4. Yamanaka et al. J Clin Oncol. 2016.

Real Patients. Real Stories.

 

When Dan's Colon Recurrence Score came back low, he decided against chemotherapy.

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