Making cancer care smarter with Oncotype DX tests

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In collaboration with thousands of physicians around the world, over one million patients improved their outcomes with the Oncotype IQ portfolio of genomic tests.

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The only genomic test proven to predict a patient’s individual benefit from chemotherapy.

For patients with early-stage, ER-positive, HER2-negative, node negative, and node-positive (1-3) breast cancer, the Oncotype DX Breast Recurrence Score quantifies the risk of distant recurrence and the likelihood of chemotherapy benefit.

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The only genomic test to quantify the risk of local recurrence (DCIS or invasive) in ductal carcinoma in situ.

For patients with ductal carcinoma in situ (DCIS) treated by local excision, with or without tamoxifen, the Oncotype DX Breast DCIS Score can help guide personalized treatment decisions.

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Decide whether immediate treatment is necessary or confidently opt for active surveillance.

For patients with clinically low-risk prostate cancer (very low, low, or intermediate NCCN risk) the Oncotype DX Genomic Prostate Score predicts the likelihood of favorable pathology (low-grade [3+3, 3+4], organ-confined disease).

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The first and only test to identify patients who will not respond to AR-targeted therapies

For patients with metastatic castration resistant prostate cancer, the Oncotype DX AR-V7 Nucleus Detect test identifies patients resistant to androgen receptor (AR) therapies such as abiraterone and enzalutamide.

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A genomic test that quantifies the risk of recurrence, for insight beyond traditional measures.

For patients with stage II or II A/B colon cancer whose tumor has been resected, the Oncotype DX Colon Recurrence score can help guide decisions about adjuvant treatment.

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The only genomic test proven to predict a patient’s individual benefit from chemotherapy.

For patients with early-stage, ER-positive, HER2-negative, node negative, and node-positive (1-3) breast cancer, the Oncotype DX Breast Recurrence Score quantifies the risk of distant recurrence and the likelihood of chemotherapy benefit.

About the Test
The only genomic test to quantify the risk of local recurrence (DCIS or invasive) in ductal carcinoma in situ.

For patients with ductal carcinoma in situ (DCIS) treated by local excision, with or without tamoxifen, the Oncotype DX Breast DCIS Score can help guide personalized treatment decisions.

About the Test
Decide whether immediate treatment is necessary or confidently opt for active surveillance.

For patients with clinically low-risk prostate cancer (very low, low, or intermediate NCCN risk) the Oncotype DX Genomic Prostate Score predicts the likelihood of favorable pathology (low-grade [3+3, 3+4], organ-confined disease).

About the Test
The first and only test to identify patients who will not respond to AR-targeted therapies

For patients with metastatic castration resistant prostate cancer, the Oncotype DX AR-V7 Nucleus Detect test identifies patients resistant to androgen receptor (AR) therapies such as abiraterone and enzalutamide.

About the Test
A genomic test that quantifies the risk of recurrence, for insight beyond traditional measures.

For patients with stage II or II A/B colon cancer whose tumor has been resected, the Oncotype DX Colon Recurrence score can help guide decisions about adjuvant treatment.

About the Test

Exact Sciences' Response to COVID-19

We want to assure you that our Oncotype DX tests remain readily available and that our laboratory continues to operate. Our patient-critical work teams continue to operate, following all safety procedures and practices.

Read the letter from our CEO

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Real People.
Real Results.

When Amy was diagnosed with breast cancer, she was scared. Her Oncotype DX Breast DCIS Score result made her feel in control.

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Healthcare Savings

How much do ineffective cancer treatments cost the healthcare system? In the US alone, Oncotype IQ tests have saved more than $3.5 billion.

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Practice Tools

The Eighth Edition AJCC Staging Manual is now effect, and it has changed staging for T1-2 N0 M0 breast cancer patients.

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Latest TAILORx Data

The landmark TAILORx results provide definitive answers on which early stage ER+, HER2-, N0 breast cancer patients can benefit from chemotherapy.

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In the US and certain other jurisdictions, Genomic Health, Oncotype, Oncotype DX, Oncotype IQ, Breast Recurrence Score, Recurrence Score, DCIS Score, Colon Recurrence Score, Genomic Prostate Score, AR-V7 Nucleus Detect, Pass It On: Until Every Woman Knows, and Making Cancer Care Smarter are registered trademarks of Genomic Health, Inc., an Exact Sciences corporation.

Making cancer care smarter.™

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Prospective Outcomes:
TAILORx

Genomics Infographic

Clinical Utility:
Active Surveillance

Clinical Comparator Trial

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Do You Really Need Chemotherapy?

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